Bristol Myers Squibb in partnership with
APA 2026 · Partner Brief

Cobenfy

BMS is showcasing Cobenfy at APA 2026. Here's the context, what to ask at the booth, and where Videra fits in the conversation.

CompanyBMS
StatusAPPROVED + Phase 3 expansions
IndicationSchizophrenia (approved Sept 2024); Phase 3 planne…
MechanismDual M1/M4 muscarinic receptor agonist (xanomeline…
Context

Why BMS is promoting this at APA

Cobenfy IS the story at APA 2026. First new mechanism of action for schizophrenia in over 30 years — every psychiatrist in the room knows about it. BMS will be promoting year-1 real-world experience, differentiation from D2 antagonists (no metabolic syndrome, no tardive dyskinesia, no prolactin elevation), and teasing the expansion indications. Their sole registered attendee is a Senior Director of US Medical Affairs — this is a high-value, evidence-focused conversation.

Booth Conversation

Talking points for the conversation

Ask about: Year-1 prescribing data and real-world experience; metabolic advantage evidence in practice; ARISE adjunctive trial follow-up (missed primary endpoint — what's next?); ADEPT-2 enrollment in Alzheimer's psychosis; bipolar I and ASD irritability trial design/timelines; formulary access and payer reception; how psychiatrists are using Cobenfy in treatment algorithms (first-line vs. switch). Their attendee James Appio (Sr. Director US Med Affairs) will want a scientifically rigorous conversation.

Videra · Med Affairs Angle

Where Videra fits

Cobenfy's first-in-class MOA needs robust RWE to prove real-world differentiation — this is year 1, the most critical evidence window. VoiceVitals captures continuous schizophrenia symptom data (speech poverty, disorganization, affective flattening) between visits. ePRO+ supports real-world outcomes measurement that goes beyond PANSS. For ADEPT-2 (AD psychosis), VoiceVitals' agitation/psychosis detection in cognitively impaired patients is directly relevant.

Position as the RWE infrastructure partner during the critical launch window. ARISE trial missed — Videra's enriched data could help identify responder subpopulations for redesigned trials.

Let's pick this up at the booth.

Set up a follow-up with BMS's team and Videra Health.

Email Ryan Roberts →